Phillipa Soo Joshua Henry MCC’s previously postponed Miscast20, an online version of the annual gala featuring Broadway stars performing songs from roles in which they would never be cast, has a new date. Tune in to Miscast20 on September 13 at 8PM ET on the MCC YouTube channel. The virtual event will benefit both MCC Theater and the Mental Health Coalition.An impressive initial list of performers has been announced and will include Adrienne Warren, Heather Headley, Rob McClure, Joshua Henry, Nicolette Robinson, Beanie Feldstein and Phillipa Soo. Seven additional performers will be announced later. The evening will also include appearances from Jocelyn Bioh, Raúl Esparza and Judith Light. Will Van Dyke will serve as the evening’s musical supervisor.“We’re extremely grateful that these incredible performers and members of our community are just as excited as we are to continue the Miscast tradition even from their homes,” said Co-Artistic Director Bernie Telsey in a statement.In addition to the performances, Miscast20 will feature a free raffle to win a table for 10 at Miscast 21 and a toast with the performers onstage after the show. Auction items available for online bidding this year include Robert LuPone’s “One” finale costume from the original production of A Chorus Line, coaching sessions with Co-Artistic Directors Will Cantler and Telsey, a private culinary experience and more. Heather Headley Beanie Feldstein Raúl Esparza Adrienne Warren(Photo: Emilio Madrid for Broadway.com) View All (9) Judith Light Rob McClure Star Files Nicolette Robinson Adrienne Warren View Comments
Sonifex is debuting a new range of DIO Audiophile Dante Interfaces today. The DIO Audiophile Dante Interfaces are plug and play devices which all allow for converting legacy connectors and signals to a Dante AoIP audio network.The line includes:XLR to DantePhono to DanteAES3 BNC to DanteTerminal block to DanteHeadphone to DanteAES3 XLR to DanteMic in to DanteAES3 terminal block to DanteHere is the line.
Feb 10, 2011New Zealand officials find vaccine helped ease 2010 flu impactSurveillance data on the impact of pandemic 2009 H1N1 influenza in New Zealand show a similar chronological progression of the disease between 2009 and 2010 but a lower impact of the disease in 2010. New Zealand officials who issued the report today in Eurosurveillance said vaccination appears to have contributed to the decreased impact. Although demographic characteristics of the 2010 wave were similar to those in 2009—with highest rates in children under 5 years and in indigenous Maori and Pacific populations—community cases, hospitalization rates, and intensive care unit (ICU) cases were all lower in 2010. Compared with 2009 rates, consultation rates in 2010 for flu-like illness were 72%, hospitalization rates 72%, and ICU admissions 87.4%. In addition, although 2010 saw fewer confirmed deaths (15), the rate of 8.5 per 100,000 cases was similar to the 2009 level of 9.0. The researchers estimated that pre-second-wave immunity to 2009 H1N1 flu, based on exposure and vaccination, ranged from 25.2% in those aged 20 to 39 to 66.6% in people 60 and older. The authors conclude, “Immunisation appears to have contributed to the reduced impact of the pandemic in 2010, particularly for those aged 60 years and older.”Feb 10 Eurosurveillance reportUK experts share early flu vaccine effectiveness findingsUK health officials today released an interim report on the effectiveness of last season’s monovalent flu vaccine and this season’s trivalent vaccine against the region’s flu strains so far, most of which has been the 2009 H1N1 virus, with some influenza B. They found that 2009 H1N1 protection was best in people who were vaccinated both seasons and that coverage seemed to wane in those who only received last season’s monovalent vaccine. Their study used data from four sentinel surveillance systems in England, Wales, and Scotland and is based on information from 4.554 people who were swabbed for flu-like illness. The study included 1,251 case-patients who tested positive for 2009 H1N1 flu and 2,229 controls, whose results were negative. Adjusted vaccine effectiveness against the 2009 H1N1 virus was 34% (95% confidence interval [CI]: -10% to 60%) for those who received only the monovalent vaccine last year, 46% (CI 7% to 69%) in those who received only the trivalent vaccine this season, and 63% (CI 37% to 78%) in those vaccinated both seasons. Against influenza B and H3N2, the adjusted vaccine effectiveness was 50% (CI 17% to 70%). The researchers said their findings were consistent with previous vaccine effectiveness findings for seasonal flu vaccines during the prepandemic years when circulating strains are a good match with the vaccine. The findings suggest a dose-response relationship to 2009 H1N1 protection, which the investigators said reinforces the importance of yearly vaccination for recommended groups.Feb 10 Eurosurveillance reportStudy: Stockpiled H5N1 vaccine useful for prime-boost strategyAn H5N1 vaccine in the US Strategic National Stockpile could be used as a powerful tool in a pandemic setting, even though the 2004 strain of the virus in it wouldn’t match current or future circulating H5N1 strains, researchers report in the Journal of Infectious Diseases. The United States currently has 20 million doses of a vaccine against the 2004 Vietnam strain of H5N1. Researchers tested different prime-boost strategies using the stockpiled vaccine alone or in combination with an experimental H5N1 vaccine that contains the Indonesian strain, the most common circulating strain. The randomized, prospective multicenter trial of 491 healthy adults also measured the effect of different time intervals between the two doses. Each dose of the H5N1 vaccine contained 90 micrograms of antigen. Immune responses using the different vaccine combinations were modest, with two doses needed to protect against a flu virus with a novel hemagglutinin antigen. A 180-day interval between the first and second dose gave the best protection but might not be an option in a quickly developing pandemic, the group reported. They concluded that giving the stockpiled Vietnam H5N1 vaccine first primed the immune system for to heighten the response to the newer vaccine. Robert Bleshe, MD, lead author of the study and director of Saint Louis University’s Center for Vaccine Development, said in a EurekAlert press release yesterday, “The most surprising thing we discovered was the value of time. It’s incredible how much stronger response you get at six months. There’s something going on there that we know nothing about and is a very interesting area for future research.”Feb 9 EurekAlert press releaseMar J Infect Dis abstractOct 31, 2007, CIDRAP News story “The pandemic vaccine puzzle part 5: what role for prepandemic vaccination?”H1N1 takes over as China’s dominant flu strainAs China enters the peak of its flu season, the 2009 H1N1 virus has edged out H3N2 as the dominant strain, the country’s health ministry said today, according to Xinhua, China’s state news agency. Shu Yuelong, head of China’s National Influenza Center, said 2009 H1N1 evolved as the dominant strain over the last 2 months, and though officials expect more severe cases to occur, the virus is not likely to have the same impact it did in 2009. The country has reported 129 severe 2009 H1N1 cases since late 2010, including 20 deaths since the start of 2011. He said confirmed flu infections and outpatient and emergency department visits for flu-like illness are all below last season’s high levels. Vaccination against the 2009 H1N1 virus also appears to be effective, he added.Feb 10 Xinhua storyHHS announces $750 million investment in public healthThe US Department of Health and Human Services (HHS) announced yesterday a $750 million investment in prevention and public health for 2011, including $137 million to help shore up public health infrastructure. The allocation, part of the Prevention and Public Health Fund established by the 2010 Affordable Care Act, “is designed to expand and sustain the necessary capacity to prevent disease, detect it early, manage conditions before they become severe, and provide states and communities the resources they need to promote healthy living,” according to an HHS release. Last year the agency distributed $500 million from the fund. This year’s spending includes $298 million for community prevention measures; $182 million for clinical prevention, which includes immunizations; $137 million for state and local public health infrastructure, including funding for disease outbreak detection and response; and $133 million on research and tracking the impact of the Affordable Care Act and other evidence-based public health measures. In a separate release today, the nonprofit Trust for America’s Health (TFAH) praised the funding, saying, “Preventing disease and injury is the most effective, common-sense way to improve health in the United States.” The fund will provide $16.5 billion over 10 years for bolstering local and state public health efforts.Feb 9 HHS press releaseFeb 9 TFAH releasePAHO investigates more AFP cases in HaitiPan American Health Organization (PAHO) officials in Haiti are investigating more potential cases of acute flaccid paralysis (AFP) in people recovering from cholera and are asking health partners to increase vigilance for the condition, the agency said yesterday in an update. Polio has been ruled out in the first four patients with AFP from Northwest department, but PAHO new suspected cases are from another department. Meanwhile, the number of new cholera cases appears to be stabilizing or even declining, and health officials have been able to turn their attention to post-earthquake activity such as rebuilding the country’s National Blood Service and a nursing school in Port-au-Prince. So far the number of confirmed cholera cases in Haiti is 216,938, including 4,120 deaths. PAHO also said mortality rates are decreasing.Feb 9 PAHO updateIn other cholera developments, scientists have described a key advance toward a better, faster test to detect the cholera toxin in sick patients, the American Chemical Society (ACS) reported yesterday. The new method uses nanoparticles that are prepared with iron oxide and coated with dextran sugar. Cholera toxin in water, blood, or other fluid binds to the nanoparticles, which can be detected by instruments. A study describing the findings appeared in the ACS journal Bioconjugate Chemistry.Feb 9 ACS press releaseBioconjug Chem abstract
Equatorial Guinea’s president calls for dialogue to end Cameroon crisis Equatorial Guinea Foreign Minister Simeon Oyono Esono Angue Equatorial Guinea has denied reports of planning to build a wall along its border with Cameroon.Equatorial Guinea Foreign Minister Simeon Oyono Esono AngueForeign minister Simeon Oyono Esono Angue said despite a diplomatic tiff between the two countries, it would be resolved through open dialogue.“The wall does not exist. The people talking about the wall lack information. When there is a problem between two countries, it is necessary to solve the problem through peaceful and diplomatic means. The media is free to propagate information, but I insist that there is no wall,” Angue told reporters in the capital of Yaounde after meeting with Cameroonian Prime Minister Joseph Dion Ngute.He said he was sent by President Teodoro Obiang Nguema Mbasogo of Equatorial Guinea to consolidate bilateral relationship which he described as “excellent” between the two countries.His remarks come after reports in early August that Equatorial Guinean soldiers had crossed the Ntem River that forms a natural border between the two countries and erected milestones in the town of Kye-Ossi on the Cameroonian side.In late July, Cameroon’s army chief Rene Claude Meka toured the 180-km border between the two countries and warned that Cameroon would not tolerate any “expansionist ambitions.”Related New bridge to be built linking Cameroon, Equatorial Guinea Emerging Equatorial Guinea
… clash with St Lucia Stars today from 16:00hrsMAINTAINING momentum will be the order of the day when the Guyana Amazon Warriors take on St Lucia Stars in their HERO Caribbean Premier League (CPL) T20 cricket match at the Guyana National Stadium, Providence, from 16:00hrs today.The local franchise, began the 2018 season in rampant fashion, whipping the St Kitts and Nevis Patriots by six wickets on Thursday evening.Guyana Amazon Warriors Head Coach Johan Botha making a point during yesterday’s pre-match press conference. Fast rising all-rounder also share the head table with Botha.Guyana bowlers have been exemplary with everyone contributing at crucial times, but it was young batting sensation, Shimron Hetmyer, who snared the limelight with a breezy, unbeaten 79, after the Amazon Warriors suffered early setbacks in the chase, losing three quick wickets inside the first three overs.Hetmyer, in only his second game announced himself on the CPL stage. His run against Bangladesh recently – 86 and 18 in the second Test and 52, 125 and 30 in the ODIs – continued as he hit nine fours and four sixes to take Guyana home with lots to spare.At a pre-match press conference yesterday at the Guyana Marriott Hotel Georgetown, head coach Johan Botha said he is expecting a tough game today, adding that the Stars will definitely want to bounce back after their opening defeat against the Trinbago Knight Riders.“I think when you got a loss you want to bounce back as quickly as you can and certainlyYoung batting sensation, Shimron Hetmyer, was the Amazon Warriors main batsman on Thursday evening.they would want to, tomorrow night (tonight), so it’s up to us to keep on top and keep the pressure on them. Having said that their lineup has some quality players as well, so we will have to bring our A game,” Botha said.On the other hand, the Stars have concerns, and although the team has been rejigged, with a new captain in Kieron Pollard, the results for St Lucia at the start of the 2018 edition clearly haven’t taken a drastic turn for the better.They are now on a 12-match losing streak stretching back to 2016, when they were called Zouks.