Startup Spotlight: Playing Pac-Man with CRISPR

first_img About the Author Reprints Meghana Keshavan By Meghana Keshavan Jan. 18, 2017 Reprints Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. Startup Spotlight: Playing Pac-Man with CRISPR What’s included? When you think of CRISPR, the suffix “Cas9” seems immediately to spring to mind. But the Cas9 enzyme isn’t the only endonuclease that could be used therapeutically, according to North Carolina-based Locus Biosciences.The startup is exploring the use of CRISPR/Cas3 in developing a new line of drugs that kill bacteria and fungi. If Cas9 works like scissors in gene editing, Cas3 is like Pac-Man — it just eats away at DNA. And it looks like it’s got its own unique set of applications. STAT chatted with Locus CEO Paul Garofolo, as well as cofounder Rodolphe Barrangou, who discovered this technology: STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. Biotech Correspondent Meghana covers biotech and contributes to The Readout newsletter. Biotech center_img @megkesh [email protected] Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+. First 30 days free. GET STARTED Alex Hogan/STAT Log In | Learn More What is it? GET STARTED Tags antibiotic resistanceCRISPRgene editingSTAT+last_img read more