Share 48 Views one comment Tweet Share Share Sharing is caring! Members of the DABAThe Dominica Amateur Basketball Association (DABA) has described its 2012 season as one of quality and great performances.At the DABA’s annual general meeting (AGM) at the Prevost Cinemall on Thursday 2nd May, president of the Association, Mickey Joseph said there is now a hype surrounding the game which is credited to last season’s performances. “The excitement and buzz about basketball last season was tremendous and we can say we had a very good season in terms of participation, not much controversy, and I think we can all be commended for putting on a good show for the basketball fans,” Mr Joseph said.DABA President Mickey JosephTwenty-four teams were registered in the 2012 basketball league.At Thursday’s meeting attended by over thirty individuals, the president noted that the association is functioning under a new constitution.Mr Joseph stated that the constitution was redesigned about two years ago to suit basketball’s international body; Fédération Internationale de Basketball Amateur (FIBA) requirements.“As part of the constitution we had to introduce the anti-doping code, which means that all members registered with the DABA have to make themselves available for any doping test that we may want to take for anybody representing the national team or even members of ordinary teams,” Mr Joseph noted.Members of the DABA at Thursday’s AGMUnder the new constitution, an executive term has moved from two years to four.During the AGM Edgar George replaced Gary Benjamin as secretary of the Association.The DABA executive is as follows: • Mickey Joseph – President• Allan Morris – Vice President• Edgar George – Secretary• Tito Aaron – Treasurer• Dustan Peters – PRO• Michael Peter – Member• Sawana Fabien – MemberVolunteers to executive• Anika Procter• Delize Paul• Shannon VidalThere are two matches scheduled for the Lindo Park hard-court from 7:00 this evening.Dominica Vibes News NewsSports DABA pleased with 2012 season by: – May 3, 2013
Scott Linton missed a penalty for Clyde after Aaron Comrie brought down Sean Higgins and they were made to pay when Montrose snatched a winner, Mallagaray slotting the ball home from Campbell’s neat pass.Leaders Elgin moved five points clear at the top of Scottish League Two as Craig Gunn’s solitary strike fired them to victory against Berwick.Elgin made a bright start, with Archie McPhee rifling a shot inches wide from 25 yards and Gunn spurning two good chances shortly afterwards.Gunn did open the scoring for the home side in the 12th minute, slamming the ball into the roof of the net. Adrian Mallagaray grabbed the winner for Montrose as they made the most of a man advantage to beat Clyde 2-1.The visitors’ afternoon got off to a sorry start as Michael Bolochoweckyj was sent off for bringing down Ross Campbell in the area when he was clean through in the 16th minute.It took a turn for the better when goalkeeper John Gibson saved Gary Fraser’s penalty and Mark McLaughlin then fired them in front from close range in the 22nd minute.But Montrose were back on level terms in first-half injury-time when trialist midfielder Jamie Clarke, released by Arbroath this week, fired into the top corner. Berwick goalkeeper Kevin Walker pulled off a superb save to deny Mark Nicolson while at the other end Darryl McHardy was on hand to volley off the line.The visitors were reduced to 10 men at the start of the second half when defender Johnny Fairbairn was sent off for elbowing Dylan Easton.Connor McLaren had the best of the late chances for Elgin as they saw out the game comfortably.Craig Watson’s header set Arbroath back to winning ways with a 2-1 Scottish League Two victory over Annan.Hamilton loan defender Watson headed the hosts into the lead a minute after the break, before Martin McNiff’s own goal (58) doubled Arbroath’s advantage.Peter Weatherson fired his 16th goal of the season in all competitions from the penalty spot late on, but the hosts were able to hold out for the win.Arbroath had pulled off three wins in a row before last weekend’s 3-2 defeat to Elgin City, but victory here set them back on track.East Fife moved level on points with second-placed Queen’s Park following a 3-1 win against East Stirling.East Stirling took an early lead when Kris Faulds’ free-kick was glanced in by the head of East Fife player-manager Gary Naysmith.It was all square in the 17th minute when Kyle Wilkie collected the ball on the left and cut inside before drilling the ball into the bottom corner.The visitors took the lead seven minutes later when Wilkie was brought down by Aron Lynas in the box. Nathan Austin’s spot-kick was saved by Richard Barnard but he slotted home the loose ball.East Stirling boss Craig Tully was sent from the sidelines by referee Gavin Ross before the break after he took umbrage with a decision.His side were on top at the start of the second half as Michael McMullin fired over the stand while East Fife’s Wilkie was wayward with another effort.The visitors wrapped up the win with three minutes remaining when a Scott Mercer corner fell to Alistair Coote and he drilled the ball into the net.Queen’s Park lost ground on League Two leaders Elgin as they were held to a goalless stalemate against Stirling at Forthbank Stadium.Willie Robertson did well to block Craig McLeish’s early shot on goal as the visitors looked to take the lead after seven minutes and Stirling lost the former to injury just after the break when he was replaced by Aurelien Mazel.Down at the other end, Mark Lamont sent his curling effort wide of the mark, while Queen’s Park goalkeeper William Muir thwarted Darren Smith. But the home side hit back with a great chance of their own from David Galt, who forced Chris Smith to tip the ball over the crossbar.The visitors lost Vincent Berry to injury before Ross Smith and namesake Darren came close for the home side but neither side was able to break the deadlock as the spoils were shared.
Source:https://www.elsevier.com/about/press-releases/research-and-journals/cocaine-use-alters-gene-expression-in-brain-reward-circuits May 31 2018A study in Biological Psychiatry has identified unique genetic changes in the brain’s reward circuitry that are associated with cocaine use, including first-time use, withdrawal, and re-exposure to the drug after prolonged withdrawal. The findings reveal important information on how cocaine addiction reprograms gene expression and provide insight into the molecular basis of cocaine addiction in unprecedented detail.In the study, mice were allowed to self-administer cocaine as a model of human addiction, and the gene expression changes were associated with their addiction-like behavior.”This study elegantly highlights the complexity of the brain’s molecular response to self-administered cocaine, pointing to mechanisms that might be targeted by treatments,” said John Krystal, Editor of Biological Psychiatry.Related StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsGene modulation goes wireless hacking the “boss gene”Revolutionary gene replacement surgery restores vision in patients with retinal degenerationPrevious studies have been limited, focusing either on specific genes, a particular brain region, or one aspect of cocaine addiction. But molecular studies aimed at improving addiction treatment have been complicated by alterations in genes that differ throughout the brain–increasing in some regions and decreasing in others.”This study is the first of its kind to characterize the global transcriptome in brain during the life-cycle of cocaine self-administration,” said senior author Eric Nestler, MD, PhD, of Icahn School of Medicine at Mount Sinai, New York. The researchers examined six regions composing the brain’s reward circuitry, providing an enormous resource of information for studying the biological basis of cocaine addiction.To characterize the entire life-cycle, Dr. Nestler and colleagues looked for differences in gene expression when mice were first exposed to cocaine; in cocaine-addicted mice after a short (24 hours) or long (30 days) period of withdrawal from the drug; and when addicted mice were re-exposed to cocaine after the 30-day withdrawal. “The experimental design thus allowed us to study how gene expression across brain reward regions changes over time as a result of volitional cocaine intake,” said Dr. Nestler.The analysis revealed changes in many transcripts involved in key biological processes, providing clues into the brain functions that might lead to cocaine addiction. Many changes were in the same direction (increased or decreased) throughout the reward circuitry, suggesting they may be good targets for new treatments. Interestingly, the size of the changes depended on the condition–where the mice were in the life-cycle of cocaine self-administration–highlighting unique gene changes associated with the different stages of drug taking. The study also identified several molecules responsible for regulating the expression of the genes associated with addiction-like behavior.