UK to test new payment model for antibiotics

first_imgIn an effort to stimulate the development of new antibiotics, Britain’s National Health Service (NHS) yesterday announced the launch of a trial for a new pilot program that will pay drug companies for antibiotics using a subscription-style model.Under the program, NHS will pay pharmaceutical companies up front for access to effective antibiotics, rather than reimbursing them based on the quantity of antibiotics sold. The idea behind the program is to delink profit from the volume sold, pay for antibiotics based on their public health value, and encourage the development of new antibiotics.Under the new model, drug makers would still be reimbursed by the NHS even if the new drugs are kept in reserve.The trial will be led by NHS and the National Institute for Health and Care Excellence (NICE). The agencies are asking pharmaceutical companies to identify antibiotics for the first phase of the program.Strong signal for rest of worldThe idea was first floated in January, when the British government announced its 5-year national action plan and 20-year vision for antimicrobial resistance (AMR). It’s a response to growing concern about the broken market for new antibiotics and the financial challenges of antibiotic development.Because new antibiotics are used for only short periods, are competing with older and cheaper drugs, and often remain on the shelf in order to hold off development of resistance, drug makers have difficulty recouping their investment and are reluctant to devote money to antibiotic research and development. As a result, many large drug companies have abandoned their antibiotic development programs, leaving the field to smaller biotech companies.UK health officials believe their model could be one solution to the problem.”Today we are sending a strong signal to the rest of the world that there are workable models to stimulate investment in these vital medicines and that together we can tackle AMR,” UK health minister Nicola Blackwood said in a press release from the UK’s Department of Health and Social Care (DHSC).The Association of the British Pharmaceutical Industry (ABPI) said in a statement that it’s looking forward to hearing more detail on the program.”Today’s announcement is an example of how the UK can lead the world in this fight and hopefully brings us closer to fixing the problems that have hampered investment in antibiotics research for so long,” Sheuli Porkess, APBI’s executive director of research, medical and innovation, said. “Patients can’t afford to wait. Our members are ready to get started, and the sooner we get this pilot up and running, the sooner we can apply what we find to other antimicrobials in development.”A positive development, but questions remainAdvocates for antibiotic development incentives will be watching the NHS pilot closely. Among them is Gregory Daniel, PhD, MPH, deputy director of the Duke-Margolis Center for Health Policy.”I think it’s a very exciting and positive development to see a government agency like the NHS announce plans to develop a subscription model like this,” Daniel told CIDRAP News. In addition to providing drug companies with a predictable, reliable payment for access to antibiotics and ensuring that effective antibiotics will be available for patients with infections, Daniel said, the subscription model could also generate positive external benefits.”By having good antibiotics on the market, patients can have invasive procedures, like surgeries, and other things that put patients at risk for an infection,” he said. “These factors don’t get addressed with traditional volume-based payment.”Daniel, who is working with colleagues at the Duke-Margolis Center for Health Policy to develop subscription models that could work in the US healthcare system (which is not nationalized like the UK’s), says he will be in interested in how the NHS values the antibiotics and calculates the subscription rate, and whether the model is paired with strong stewardship programs that ensure the antibiotics are being used appropriately.He’ll also be watching to see whether the program actually motivates drug companies to devote money to developing new antibiotics. “The third question is, ‘Does this actually change the economic situation for the companies?'” he said.See also:Jul 9 DHSC press releaseJul 9 APBI statementJan 24 CIDRAP News story “UK aims to cut antibiotics 15% in 5-year AMR plan”last_img read more

Museum of Liverpool case: What went wrong?

first_imgStay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our community Get your free guest access  SIGN UP TODAY Subscribe now for unlimited access To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGINlast_img read more

KSRM Week In Review 6/22 – 6/26

first_imgSoldotna Mayor Considers Stint in Africa, BBB Warns Alaskans of Charity Scams Amidst Wildfires, Peninsula Ranks High For Local Hire, Multiple Guns Stolen From Nikiski Residence Wednesday 6/24 FacebookTwitterEmailPrintFriendly分享The KSRM News Department compiled some of the top stories from this past week. LNG Expert Fears Project May Miss Window of Opportunity, Firefighter Injured in Encounter with Bear, ENSTAR Restores Service to Portions of Kenai Keys, Public Comment Period Open on KNWR Proposed Public Use Changes ENSTAR Gas Cost Dropping 11.9%, Power Restored to 22,000 HEA Members, Body Found in Trail Lake Presumed Missing Nevada Canoeist, Hilcorp Pursues New Road-Accessible Drill Pad in Ninilchik Unit Thursday 6/25 Walker Mulls TransCanada Buy-Out, No Bait for Kings July 1, 36-Hrs for Commercial Fisheries, Baking with Gratitude for Card St Fire Fighters, Alaska to Rename Wade Hampton Census Area Friday 6/26 Tuesday 6/23 Monday 6/22 Study Finds 26% of Alaskan Infant Deaths Preventable, Increased Water Usage Results in Kenai Resident Notices, Ketchikan Mourns 9 Lost as Officials Initiate Recovery Efforts, PRL, The Cannery Lodge Named Kenai Business of the Yearlast_img read more

Fudo takes charge at Vernal Ladies

first_imgASAKURA, Fukuoka Pref. – Yuri Fudo shot a bogey-free 7-under 65 to take a three-stroke lead over South Korean Jeon Mi Jeong after the second round of the Vernal Ladies on Saturday. Fudo, who won six consecutive Japan LPGA money titles through 2005, made three birdies on the front nine and added four more after the turn to sit atop the leaderboard at 8-under 136. “I was lucky today. Even if I thought I had bad shots, they turned out all right,” Fudo said. “This year, I’ve faltered late in tournaments, so I won’t think about winning and just try to stay away from bogeys.” GET THE BEST OF THE JAPAN TIMES IN FIVE EASY PIECES WITH TAKE 5last_img

Nonprofit Museum Speaks Out Against New AntiLGBT Law—But Is That Its Mission

first_imgShareTweet2ShareEmail2 SharesNeuberger Museum of Art, Purchase, New York / Lee CannonApril 5, 2016; HyperallergicWith businesses and government speaking out about the recent rash of attempts to pass laws that discriminate against LGBTQ people, there is still plenty of room for nonprofits to be heard on the subject, even those with missions that are not focused in that way. Here is one example.Although the Neuberger Museum of Art lent the pieces to be displayed to the Mississippi Museum of Art in “When Modern Was Contemporary,” an exhibit due to open on April 9th, its director, Dr. Tracy Fitzpatrick, and the president of Purchase State College in New York, Thomas J. Schwarz, will sit out the opening in response to Mississippi Governor Phil Bryant’s signing of the Religious Liberty Accommodations Act into law. Mississippi is the third state after Kansas and North Carolina to recently pass an explicitly anti-LGBTQ bill.There are 52 artists featured in the exhibit, including Jackson Pollock, Marsden Hartley, Jacob Lawrence, Georgia O’Keeffe, and Mark Rothko.Here is a statement from Fitzpatrick:At the Neuberger Museum of Art, we are delighted that the residents of Mississippi will be afforded the extraordinary opportunity to view works by some of America’s most important 20th century artists from our collection in “When Modern Was Contemporary: Selections from the Roy R. Neuberger Collection.” This exhibition reflects the ways in which our founding patron, Roy R. Neuberger, supported living artists irrespective of their backgrounds and beliefs, and valued open dialogue through a mix of ideas—even those that were controversial and unpopular, an approach that is in opposition to Mississippi’s new, sweeping, discriminatory anti-gay and transgender legislation.As an academic art museum our role is to educate diverse audiences in and through the visual arts by presenting a variety of media and cultural perspectives, and works by artists from diverse backgrounds and convictions. While I hope that the presence of the works by such a diverse group of artists in “When Modern Was Contemporary” will help create dialogue around these issues, in view of Mississippi’s new discriminatory law it is with great regret that I must decline the Mississippi Museum of Art’s kind invitation to celebrate with them on the occasion of the opening of the Neuberger exhibition.In keeping with its values, the Neuberger Museum hopes that its newly opened exhibition, “Louise Fishman: A Retrospective,” will also contribute to this dialogue in a meaningful way. The exhibition is the first career survey of this important American artist who has long fought for the meaningful recognition that we believe has eluded her and many women artists because of sexism and anti-gay bias. Hopefully, both the Louise Fishman exhibition and When Modern Was Contemporary will stimulate comment and thoughtful dialogue as many in the nation struggle to achieve a greater climate of acceptance and equality. Many of the programs associated with the Louise Fishman exhibition will focus on LGBTQ issues.Let that be a model for you and yours.—Ruth McCambridgeShareTweet2ShareEmail2 Shareslast_img read more